genocad

teaching-genocad

Teaching Synthetic Biology with GenoCAD

Teaching synthetic biology can be challenging because it involves concepts from so many fields.  I would like to give credit to two professors who have been teaching synthetic biology using GenoCAD. I was directly involved in the class taught by Massimiliano...

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Sustainability of bioinformatics infrastructures

GenomeWeb published a long article about the sustainability of bioinformatics infrastructures based on the GenoCAD transition into a commercial product. The articles describes the challenges of finding the right business model allowing the scientific community who depends on the tools...

Virginia Tech announces GenoCAD transition

Virginia Tech issued a press-release announcing the transformation of GenoCAD into a commercial product. GenoCAD started as a NSF-funded research project. In 2010, we released the application open-source using the Apache 2.0 license. Open source licensing appeared to be the...

Plant Synthetic Biology

Plant Synthetic Biology

Plant synthetic biology requires software tools to assist on the design of complex multi-genic expression plasmids. Here a vector design strategy to express genes in plants is formalized and implemented as a grammar in GenoCAD, a Computer-Aided Design software that...

Database of standard biological parts derived from plasmid features

Database of standard biological parts derived from plasmid features

Synthetic biologists rely on databases of standard biological parts to design genetic devices and systems. The Registry of Standard Biological Parts and other community resources provide the sequences and descriptions of thousands of genetic parts. The content of these database  is often...

GenoCAD has Moved!

GenoCAD has not been supported by an active research grant since 2013. As a result, the Virginia Bioinformatics Institute no longer has the resources necessary to maintain this free service to the community. Last we week we redirected the GenoCAD.org address...

Database of biological parts

Nucleic Acids Research just published a paper describing the results of our efforts to analyze the annotations of thousands of plasmids commonly used across many life science specialties. This effort allowed us to release a database of genetic parts and...

Cloning forever

No design needed! Over the last six months, I spent considerable time and efforts trying to engage biologists in discussions about the design of expression vectors. My goal has been to better understand the design rules applicable in different domains...

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